Droplet Chips
Droplet chips
Dolomite offers a wide range of Droplet Chips with different junction geometries, channel sizes and surface properties. All Droplet Chips have excellent optical transparency for clear imaging of droplets. Advanced hydrophobic coating treatments enable water-in-oil droplets to be generated as well as oil-in-water droplets formed in the untreated chips.
Dolomite is a licensee of Japan Science and Technology Agency ("JST") under JST's microdroplet generation technology. This enables our customers to purchase and use our droplet chips for R&D purposes without any restriction from this comprehensive IP family.
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18 micron Droplets generated in the Dolomite Small Droplet Chip |
30 micron Droplets generated in the Dolomite Small Droplet Chip |
Droplet Junction Chip 100µm or 190µm etch depth available in normal or hydrophobic versions
Part Number 100 µm etch depth: 3000158
Part Number 190 µm etch depth: 3000436
Part Number 100 µm etch depth hydrophobic : 3000301
Part Number 190 µm etch depth hydrophobic: 3000437
The Droplet Junction Chip is a glass microfluidic device designed for generating droplets. The Droplet Junction Chip offers both a T- and X-Junction. Applications include monodispersed droplet formation and emulsion formation.
Features and benefits:
Easy to use
- Extremely high droplet production rate of up to 12,000 droplets per second
- Extremely consistent droplet size
- Straight-through path for droplets
- Excellent visibility
- Hydrophilic coating; also available with hydrophobic coating
- Excellent chemical compatibility
- Wide temperature and pressure range
- Compatible with Chip Interface H for fluidic connection
- Operating pressure: 30bar
Available in both 100 and 190µm etch depth and both normal and hydrophobic versions.
The additional following options are available:
- Top layer or base layer left un-etched to create a semi-circular channel cross-section.
- Top layer and/or base layer etched to different depths.
- Quartz chips for improved optical transmission.
Double Chip Interface H
Part Number: 3200088
The Double Chip Interface H provides the capability to directly interface 2 chips together and is designed for use with the Linear Connector 4-way (Part No. 3000024) to provide eight fluidic connections to 1.6mm OD tubing. An interface between 2 chips of dimensions 22.5 x 15 x 4mm is achieved via a precision perfluoroelastomer gasket aligned with the microchannels. One key application of the Double Chip Interface H is in double emulsion generation. This requires one hydrophilic Droplet Junction Chip (Part No. 3000158 or 3000436) and one hydrophobic Droplet Junction Chip (Part No. 3000301 or 3000437) for the production of droplets inside droplets.
Features and benefits:
- Chip thickness: 4mm
- Chip width: 15mm
- Number of interface ports: 4
- Number of tubing ports: 8
- Operation pressure: 10bar
- Operation temperature of seals and gasket: -15°C to 250°C
- Provides a microchannel to microchannel connection between 2 chips
- Enables microfluidic paths with different surface treatments to be created
- Platform for double emulsion generation
- Excellent chemical compatibility
- Low dead volume connections
- Quick to connect/disconnect
- High visibility (excellent access for optics)
Droplet Junction Chip with header available in both 100 and 190µm etch depth and both normal and hydrophobic versions.
Part Number 100µm etch depth: 3200089
Part Number 190µm etch depth: 3200091
Part Number 100µm etch depth hydrophobic: 3200090
Part Number 190µm etch depth hydrophobic: 3200092
The Droplet Junction Chip with header is a glass microfluidic device designed for generating droplets. The Droplet Junction Chip is available with attached header for ejection of droplets into a bulk liquid. This is useful for generation of emulsions since it reduces the likelihood of droplet coalescence, which can be an issue with some fluids on transfer from chip to tubing. In this configuration, the Droplet Junction Chip with Header is used with the Linear Connector 4-way to generate droplets on the X-junction and eject from the edge of the chip. Droplets can be collected using the Droplet Collection Module An additional benefit of this collection method is that droplets can be cured with UV light immediately after generation.
Features and benefits:
- Easy to use
- Extremely high droplet production rate of up to 12,000 droplets per second
- Extremely consistent droplet size
- Straight-through path for droplets
- 100µm or 190µm etch depth
- Hydrophilic coating; also available with hydrophobic coating
- Excellent visibility
- Excellent chemical compatibility
- Wide temperature and pressure range
- Compatible with Chip Interface H for fluidic connection
- Operating pressure: 30bar
Available in both 100 and 190µm etch depth and both normal and hydrophobic versions.
Droplet Generation Chip with header available in both 50µm and 100µm etch depth and both normal and hydropobic versions.
Part Number 50µm etch depth: 3000048
Part Number 100µm etch depth: 3000211
Part Number 50µm etch depth hydrophobic: 3200161
Part Number 100µm etch depth hydrophobic: 3200123
The Droplet Generation Chip with header is a glass microfluidic device designed for generating droplets made up of one, two or three reagents. Applications include monodispersed droplet formation, emulsion formation and Janus particle formation. The chip is supplied with a location pin that allows connection to the Circular Connector (Part No. 3000051).
Features and benefits:
- Quick and easy to connect and release
- Extremely high droplet production rate
- Extremely consistent droplet size
- Automatic alignment of connections
- Excellent visibility
- Available with hydrophobic and hydrophilic coating
- Excellent chemical compatibility
- Wide temperature and pressure range
- Operating pressure: 20bar
- 4 inputs and 2 outputs
- Requires a Circular Connector
Available in both 50µm and 100µm etch depth and both normal and hydropobic versions.
Chip Interface H
Part Number: 3000155
The Chip Interface H works in conjunction with two Linear Connectors 4-way, providing fluidic connections to glass microfluidic chips.
Features and benefits:
- Flexible solution - compatible with chips of dimensions
- 22.5 x 15.0 x 4.0mm
- Enables fast and reliable connections between Dolomite chips and 1.6mm tubing
- Small footprint
- High chemical resistance
- Variable I.D./O.D. pipe connection
- Low dead volume
- Wide temperature and pressure range
Quartz Droplet Junction Chip available in both 100µm and 190µm etch depth and both normal and hydropobic versions.
Part Number 100µm etch depth: 3200130
Part Number 190µm etch depth: 3200132
Part Number 100µm etch depth hydrophobic: 3200131
Part Number 190µm etch depth hydrophobic: 3200133
The Quartz Droplet Junction Chip is a microfluidic device designed for generating droplets. The Quartz Droplet Junction Chip offers both a T- and X-Junction. Applications include monodispersed droplet formation and emulsion formation.
Features and benefits:
- Easy to use
- Extremely high droplet production rate of up to 12,000 droplets per second
- Extremely consistent droplet size
- Straight-through path for droplets
- Excellent visibility
- Hydrophilic coating; also available with hydrophobic coating
- Excellent chemical compatibility
- Wide temperature and pressure range
- Compatible with Chip Interface H (Part No. 3000155) for fluidic connection
- Operating pressure: 30bar
Quartz Droplet Junction Chip are available in both 100µm and 190µm etch depth and both normal and hydropobic versions.
The following custom options are available:
- Top layer or base layer left un-etched to create a semi-circular channel cross-section.
- Top layer and/or base layer etched to different depths.
Small Droplet Chip 14µm etch depth available in normal and hydrophobic versions
Part Number 14µm etch depth: 3200136
The Small Droplet Chip is a glass microfluidic device designed for generating small droplets in the size range of 5-30µm. The Small Droplet Chip offers a flow focussing junction geometry with 14 x 17µm cross-section at the junction. Applications are found in drug delivery, materials science and food research where smaller droplets allow for the improved control over the targeting and release of active compounds.
Features and benefits:
- Rapid generation of small droplets in the 5-30µm size range
- Ideal for producing and analysing micro-emulsions
- Near-circular microchannel profile at the junction for stable droplet generation
- Hydrophobic surface coating
- On-chip filters on inlet channels to prevent blockages
- Generates highly monodisperse droplets when used with the Droplet Advanced System
- Excellent chemical compatibility
- Compatible with Dolomite connectors for quick and reliable fluidic connection
- Operating pressure: 30bar
Available in both normal and hydrophobic versions.
