The Vena8™ biochip with/without glass coverslip adhered; with/without treatment for cell rolling and adhesion on proteins; seeding of cells or microbes and subsequent study of drug interaction, imaging or molecular biology studies under shear flow. Compatible with brightfield, phase contrast imaging, immunofluorescence and confocal microscopy.

Features:

• Cell rolling and adhesion on proteins; seeding of cells or microbes and subsequent study of drug interaction, imaging or molecular biology studies under shear flow.
• Biochips are supplied with or without glass coverslip attached. 
• Glass coverslip may be treated or non-treated; e.g. glass may be treated with chelated Cu2+ ion tethered to the high-density PEG coating - surface of the microchannels may then be easily coated via pipetting and the protein binds via the poly-histidine tag.
• Biochips available for low or high flow rates / shear stresses.
• Ideal for whole blood, primary cells, rare cells e.g. where samples are more difficult to retrieve or culture or only small sample volumes available.
• Perfect for high flow rates / high shear stresses e.g. platelet adhesion, aggregation and thrombi formation studies for thrombosis using whole blood. In standard flow chambers / perfusion chambers; significant volumes of blood would be required making the assay impossible.
• Suitable for biofilm applications; particularly Vena8 biochips supplied without glass coverslip: user may attach any type of coupon to bottom of the biochip.
• No assembly of the biochip is required unlike many standard perfusion chambers / flow chambers.
• No luer lock connections which increase dead volume. Cellix's biochips have a unique plug & play connection with tubing connections which are autoclaveable and reuseable.

Applications: Flow assays using minimal sample volumes (whole blood, cell suspensions, proteins etc.); immunofluorescence and confocal microscopy.